Patient-ventilator asynchrony as a predictor of weaning failure in mechanically ventilated COPD patients

Abstract Background Patient-ventilator asynchrony is a common problem in mechanically ventilated patients. It associated with adverse effects including increased work of breathing, patient discomfort, need for sedation, prolonged mechanical ventilation, weaning difficulties, and failure. The purpose the present was to describe patient-ventilator its impact on outcomes chronic obstructive pulmonary disease (COPD) Results One hundred COPD patients were enrolled this prospective study. Weaning failure (need NIV or reintubation within 48 h) noticed 27 (27%) while 73 (73%) had successful weaning. Patients failed significantly higher index (A.I) ineffective trigger (ITI) comparison those (7.69 ± 3.71, 3.46 2.59 versus 6.27 3.14, 2.47 2.08, respectively; P value< 0.04). Data expressed as mean standard deviation. Conclusion High high may be early predictors